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Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells
Collagen is the most abundant protein in animals. Its overproduction is associated with fibrosis and cancer metastasis. The stability of collagen relies on post-translational modifications, the most prevalent being the hydroxylation of collagen strands by collagen prolyl 4-hydroxylases (CP4Hs). Cata...
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| Опубликовано в: : | ACS Chem Biol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4798942/ https://ncbi.nlm.nih.gov/pubmed/26535807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00749 |
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