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Targeting Sphingosine-1-Phosphate Signaling in Lung Diseases
Sphingosine-1- phosphate (S1P), a simple, bioactive sphingolipid metabolite, plays a key role, both intracellularly and extracellularly, in various cellular processes such as proliferation, survival, migration, inflammation, angiogenesis, and endothelial barrier integrity. The cellular S1P level is...
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| Veröffentlicht in: | Pharmacol Ther |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5140735/ https://ncbi.nlm.nih.gov/pubmed/27621206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2016.09.008 |
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