Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair

Lung alveolar epithelium is composed of alveolar type I (AT1) and type II (AT2) cells. AT1 cells mediate gas exchange, whereas AT2 cells act as progenitor cells to repair injured alveoli. Lung microvascular endothelial cells (LMVECs) play a crucial but still poorly understood role in regulating alve...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Chen, Qian, Rehman, Jalees, Chan, Manwai, Fu, Panfeng, Dudek, Steven M., Natarajan, Viswanathan, Malik, Asrar B., Liu, Yuru
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371431/
https://ncbi.nlm.nih.gov/pubmed/32610129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107828
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