Targeting B-cell malignancies through human B-cell receptor specific CD4(+) T cells

The B-cell receptor (BCR) expressed by a clonal B cell tumor is a tumor specific antigen (idiotype). However, the T-cell epitopes within human BCRs which stimulate protective immunity still lack detailed characterization. In this study, we identified 17 BCR peptide-specific CD4(+) T-cell epitopes de...

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Vydáno v:Oncoimmunology
Hlavní autoři: Weng, Jinsheng, Baio, Flavio Egidio, Moriarty, Kelsey E., Torikai, Hiroki, Wang, Hua, Liu, Zhiqiang, Maiti, Sourindra N., Gwak, Dongho, Popescu, Michael S., Cha, Soung-Chul, Cooper, Laurence J. N., Neelapu, Sattva S., Kwak, Larry W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139634/
https://ncbi.nlm.nih.gov/pubmed/27999743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1232220
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