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Targeting human B-cell malignancies through Ig light chain specific cytotoxic T lymphocytes

PURPOSE: The variable regions of Ig (idiotype, Id) expressed by malignant B cells can be used as tumor-specific antigens that induce humoral and cellular immunity. However, epitopes derived from Id that stimulate human CD8+ T-cell immunity are incompletely characterized. EXPERIMENTAL DESIGN: The clo...

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Detalhes bibliográficos
Main Authors: Weng, Jinsheng, Cha, Soung-Chul, Matsueda, Satoko, Alatrash, Gheath, Popescu, Michael S., Yi, Qing, Molldrem, Jeffrey J, Wang, Michael, Neelapu, Sattva S., Kwak, Larry W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176952/
https://ncbi.nlm.nih.gov/pubmed/21813633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0970
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