Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers

BACKGROUND: Measures of spatial intratumor heterogeneity are potentially important diagnostic biomarkers for cancer progression, proliferation, and response to therapy. Spatial relationships among cells including cancer and stromal cells in the tumor microenvironment (TME) are key contributors to he...

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Vydáno v:J Pathol Inform
Hlavní autoři: Spagnolo, Daniel M., Gyanchandani, Rekha, Al-Kofahi, Yousef, Stern, Andrew M., Lezon, Timothy R., Gough, Albert, Meyer, Dan E., Ginty, Fiona, Sarachan, Brion, Fine, Jeffrey, Lee, Adrian V., Taylor, D. Lansing, Chennubhotla, S. Chakra
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications & Media Pvt Ltd 2016
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139455/
https://ncbi.nlm.nih.gov/pubmed/27994939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2153-3539.194839
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