Localization of the estrogen-binding site of alpha-fetoprotein in the chimeric human-rat proteins.
Rat alpha-fetoprotein (AFP) has been demonstrated to bind estrogen, whereas human AFP lacks the activity. We constructed four chimeric molecules from cDNAs encoding these AFPs with the use of two restriction sites common to them and expressed them as well as rat and human AFP cDNA in yeast. The reco...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1707533/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.8.3102 |
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