Localization of the estrogen-binding site of alpha-fetoprotein in the chimeric human-rat proteins.

Rat alpha-fetoprotein (AFP) has been demonstrated to bind estrogen, whereas human AFP lacks the activity. We constructed four chimeric molecules from cDNAs encoding these AFPs with the use of two restriction sites common to them and expressed them as well as rat and human AFP cDNA in yeast. The reco...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Nishi, S, Matsue, H, Yoshida, H, Yamaoto, R, Sakai, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1707533/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.8.3102
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