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Identification of critical paralog groups with indispensable roles in the regulation of signaling flow

Extensive cross-talk between signaling pathways is required to integrate the myriad of extracellular signal combinations at the cellular level. Gene duplication events may lead to the emergence of novel functions, leaving groups of similar genes - termed paralogs - in the genome. To distinguish crit...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Modos, Dezso, Brooks, Johanne, Fazekas, David, Ari, Eszter, Vellai, Tibor, Csermely, Peter, Korcsmaros, Tamas, Lenti, Katalin
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138592/
https://ncbi.nlm.nih.gov/pubmed/27922122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38588
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