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Identification of critical paralog groups with indispensable roles in the regulation of signaling flow

Extensive cross-talk between signaling pathways is required to integrate the myriad of extracellular signal combinations at the cellular level. Gene duplication events may lead to the emergence of novel functions, leaving groups of similar genes - termed paralogs - in the genome. To distinguish crit...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Modos, Dezso, Brooks, Johanne, Fazekas, David, Ari, Eszter, Vellai, Tibor, Csermely, Peter, Korcsmaros, Tamas, Lenti, Katalin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138592/
https://ncbi.nlm.nih.gov/pubmed/27922122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38588
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