Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies

Even targeted chemotherapies against solid cancers show a moderate success increasing the need to novel targeting strategies. To address this problem, we designed a systems-level approach investigating the neighbourhood of mutated or differentially expressed cancer-related proteins in four major sol...

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Udgivet i:NPJ Syst Biol Appl
Main Authors: Módos, Dezső, Bulusu, Krishna C., Fazekas, Dávid, Kubisch, János, Brooks, Johanne, Marczell, István, Szabó, Péter M., Vellai, Tibor, Csermely, Péter, Lenti, Katalin, Bender, Andreas, Korcsmáros, Tamás
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460138/
https://ncbi.nlm.nih.gov/pubmed/28603644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-017-0003-6
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