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Sustained delivery of vincristine inside an orthotopic mouse sarcoma model decreases tumor growth

BACKGROUND: Sarcoma accounts for 20% of solid tumors in children. Surgery has significant morbidity. We hypothesized that delivering chemotherapy directly into tumors through sustained release silk systems could slow tumor growth. METHODS: Human Ewing sarcoma cells A673 were cultured with vincristin...

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Detalles Bibliográficos
Publicado en:J Pediatr Surg
Main Authors: Harris, Jamie C., Coburn, Jeannine M., Kajdacsy-Balla, Andre, Kaplan, David L., Chiu, Bill
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138133/
https://ncbi.nlm.nih.gov/pubmed/27680598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2016.09.040
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