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Manipulation of variables in local controlled release vincristine treatment in neuroblastoma
INTRODUCTION: Local drug delivery minimizes systemic toxicity while delivering high-dose chemotherapy for neuroblastoma patients. We hypothesized that varying burst and maintenance dosing of implanted silk platforms would improve survival. METHODS: Platforms were loaded with vincristine 25µg, 50µg,...
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| Veröffentlicht in: | J Pediatr Surg |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5723549/ https://ncbi.nlm.nih.gov/pubmed/28927981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2017.08.028 |
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