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Manipulation of variables in local controlled release vincristine treatment in neuroblastoma

INTRODUCTION: Local drug delivery minimizes systemic toxicity while delivering high-dose chemotherapy for neuroblastoma patients. We hypothesized that varying burst and maintenance dosing of implanted silk platforms would improve survival. METHODS: Platforms were loaded with vincristine 25µg, 50µg,...

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Publicat a:J Pediatr Surg
Autors principals: Coburn, Jeannine M., Harris, Jamie, Cunningham, Rachel, Zeki, Jasmine, Kaplan, David L., Chiu, Bill
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723549/
https://ncbi.nlm.nih.gov/pubmed/28927981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2017.08.028
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