Effects of rs3846662 Variants on HMGCR mRNA and Protein Levels and on Markers of Alzheimer’s Disease Pathology

3-Hydroxy-3-methyglutaryl coenzyme A reductase (HMGCR) is a cholesterol-regulating gene with statin relevance. rs3846662 being involved in regulation of HMGCR alternative splicing, we explored its impact on HMGCR messenger RNA (mRNA) and protein levels in the brain and the associations between those...

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Bibliografiska uppgifter
I publikationen:J Mol Neurosci
Huvudupphovsmän: Leduc, Valerie, Théroux, Louise, Dea, Doris, Dufour, Robert, Poirier, Judes
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138059/
https://ncbi.nlm.nih.gov/pubmed/26541602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-015-0666-7
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