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Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer’s disease

The discovery that the apolipoprotein E (apoE) ε4 allele is genetically linked to both sporadic and familial late-onset Alzheimer’s disease (AD) raises the possibility that a dysfunction of the lipid transport system could seriously affect lipid homeostasis in the brain of AD subjects. The presence...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Poirier, Judes, Miron, Justin, Picard, Cynthia, Gormley, Patrick, Théroux, Louise, Breitner, John, Dea, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140289/
https://ncbi.nlm.nih.gov/pubmed/24973118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.03.037
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