Multiple nanoemulsion system for an oral combinational delivery of oxaliplatin and 5-fluorouracil: preparation and in vivo evaluation

Oxaliplatin (OXA) is a third-generation cisplatin analog that has been approved as first-line chemotherapy in combination with 5-fluorouracil (5-FU) for the treatment of resectable and advanced colorectal cancer. However, the therapeutic efficacy of oral OXA and 5-FU is limited by their low bioavail...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Pangeni, Rudra, Choi, Sang Won, Jeon, Ok-Cheol, Byun, Youngro, Park, Jin Woo
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138023/
https://ncbi.nlm.nih.gov/pubmed/27942212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S121114
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