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Loading cisplatin onto 6-mercaptopurine covalently modified MSNS: a nanomedicine strategy to improve the outcome of cisplatin therapy

In the treatment of cancer patients, cisplatin (CDDP) exhibits serious cardiac and renal toxicities, while classical combinations related to CDDP are unable to solve these problems and may result in worse prognosis. Alternately, this study covalently conjugated 6-mercaptopurine (6MP) onto the surfac...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Lv, Xiaojie, Zhao, Ming, Wang, Yuiji, Hu, Xi, Wu, Jianhui, Jiang, Xueyun, Li, Shan, Cui, Chunying, Peng, Shiqi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138022/
https://ncbi.nlm.nih.gov/pubmed/27942204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S116286
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