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Preparation, Characterization, Pharmacokinetic, and Therapeutic Potential of Novel 6-Mercaptopurine-Loaded Oral Nanomedicines for Acute Lymphoblastic Leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common hematologic malignancy in children. It requires a long and rigorous course of chemotherapy treatments. 6-Mercaptopurine (6-MP) is one of the primary drugs used in chemotherapy. Unfortunately, its efficacy has been limited due to its i...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zou, Yaru, Mei, Dong, Yuan, Jinjie, Han, Jiaqi, Xu, Jiamin, Sun, Ning, He, Huan, Yang, Changqing, Zhao, Libo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886780/
https://ncbi.nlm.nih.gov/pubmed/33603372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S290466
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