Loading cisplatin onto 6-mercaptopurine covalently modified MSNS: a nanomedicine strategy to improve the outcome of cisplatin therapy

In the treatment of cancer patients, cisplatin (CDDP) exhibits serious cardiac and renal toxicities, while classical combinations related to CDDP are unable to solve these problems and may result in worse prognosis. Alternately, this study covalently conjugated 6-mercaptopurine (6MP) onto the surfac...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Lv, Xiaojie, Zhao, Ming, Wang, Yuiji, Hu, Xi, Wu, Jianhui, Jiang, Xueyun, Li, Shan, Cui, Chunying, Peng, Shiqi
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138022/
https://ncbi.nlm.nih.gov/pubmed/27942204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S116286
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