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Critical differences between induced and spontaneous mouse models of Graves’ disease with implications for antigen-specific immunotherapy in humans

Graves’ hyperthyroidism, a common autoimmune disease caused by pathogenic autoantibodies to the thyrotropin (TSH) receptor, can be treated but not cured. This single autoantigenic target makes Graves’ disease a prime candidate for antigen-specific immunotherapy. Previously, in an induced mouse model...

詳細記述

保存先:
書誌詳細
出版年:J Immunol
主要な著者: Rapoport, Basil, Banuelos, Bianca, Aliesky, Holly A, Trier, Nicole Hartwig, McLachlan, Sandra M
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137841/
https://ncbi.nlm.nih.gov/pubmed/27913646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601393
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