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Critical differences between induced and spontaneous mouse models of Graves’ disease with implications for antigen-specific immunotherapy in humans
Graves’ hyperthyroidism, a common autoimmune disease caused by pathogenic autoantibodies to the thyrotropin (TSH) receptor, can be treated but not cured. This single autoantigenic target makes Graves’ disease a prime candidate for antigen-specific immunotherapy. Previously, in an induced mouse model...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137841/ https://ncbi.nlm.nih.gov/pubmed/27913646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601393 |
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