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Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers
Tumor genomes are mosaics of somatic structural variants (SVs) that may contribute to the activation of oncogenes or inactivation of tumor suppressors, for example, by altering gene copy number amplitude. However, there are multiple other ways in which SVs can modulate transcription, but the general...
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| I publikationen: | Proc Natl Acad Sci U S A |
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| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137778/ https://ncbi.nlm.nih.gov/pubmed/27856756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606220113 |
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