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Ligand-induced and small-molecule control of substrate loading in a hexameric helicase
Processive, ring-shaped protein and nucleic acid protein translocases control essential biochemical processes throughout biology and are considered high-prospect therapeutic targets. The Escherichia coli Rho factor is an exemplar hexameric RNA translocase that terminates transcription in bacteria. A...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137764/ https://ncbi.nlm.nih.gov/pubmed/27821776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616749113 |
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