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Modification of orthogonal tRNAs: unexpected consequences for sense codon reassignment
Breaking the degeneracy of the genetic code via sense codon reassignment has emerged as a way to incorporate multiple copies of multiple non-canonical amino acids into a protein of interest. Here, we report the modification of a normally orthogonal tRNA by a host enzyme and show that this adventitio...
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| 發表在: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137457/ https://ncbi.nlm.nih.gov/pubmed/27915288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw948 |
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