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Thioredoxin fusion construct enables high-yield production of soluble, active matrix metalloproteinase-8 (MMP-8) in Escherichia Coli

Matrix metalloproteinases (MMPs) are crucial proteases in maintaining the health and integrity of many tissues, however their dysregulation often facilitates disease progression. In disease states these remodeling and repair functions support, for example, metastasis of cancer by both loosening the...

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Bibliografiske detaljer
Udgivet i:Protein Expr Purif
Main Authors: McNiff, M.L., Haynes, E.P., Dixit, N., Gao, F.P., Laurence, J.S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137367/
https://ncbi.nlm.nih.gov/pubmed/26923061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2016.02.012
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