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Thioredoxin fusion construct enables high-yield production of soluble, active matrix metalloproteinase-8 (MMP-8) in Escherichia Coli

Matrix metalloproteinases (MMPs) are crucial proteases in maintaining the health and integrity of many tissues, however their dysregulation often facilitates disease progression. In disease states these remodeling and repair functions support, for example, metastasis of cancer by both loosening the...

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Detalles Bibliográficos
Publicado en:Protein Expr Purif
Autores principales: McNiff, M.L., Haynes, E.P., Dixit, N., Gao, F.P., Laurence, J.S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137367/
https://ncbi.nlm.nih.gov/pubmed/26923061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2016.02.012
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