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The N14 anti-afamin antibody Fab: a rare V(L)1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling

The monoclonal antibody N14 is used as a detection antibody in ELISA kits for the human glycoprotein afamin, a member of the albumin family, which has recently gained interest in the capture and stabilization of Wnt signalling proteins, and for its role in metabolic syndrome and papillary thyroid ca...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Acta Crystallogr D Struct Biol
Main Authors: Naschberger, Andreas, Fürnrohr, Barbara G., Lenac Rovis, Tihana, Malic, Suzana, Scheffzek, Klaus, Dieplinger, Hans, Rupp, Bernhard
פורמט: Artigo
שפה:Inglês
יצא לאור: International Union of Crystallography 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137224/
https://ncbi.nlm.nih.gov/pubmed/27917827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S205979831601723X
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