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The N14 anti-afamin antibody Fab: a rare V(L)1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling

The monoclonal antibody N14 is used as a detection antibody in ELISA kits for the human glycoprotein afamin, a member of the albumin family, which has recently gained interest in the capture and stabilization of Wnt signalling proteins, and for its role in metabolic syndrome and papillary thyroid ca...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Struct Biol
Main Authors: Naschberger, Andreas, Fürnrohr, Barbara G., Lenac Rovis, Tihana, Malic, Suzana, Scheffzek, Klaus, Dieplinger, Hans, Rupp, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137224/
https://ncbi.nlm.nih.gov/pubmed/27917827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S205979831601723X
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