New Insights into Molecular Organization of Human Neuraminidase-1: Transmembrane Topology and Dimerization Ability

Neuraminidase 1 (NEU1) is a lysosomal sialidase catalyzing the removal of terminal sialic acids from sialyloconjugates. A plasma membrane-bound NEU1 modulating a plethora of receptors by desialylation, has been consistently documented from the last ten years. Despite a growing interest of the scient...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Maurice, Pascal, Baud, Stéphanie, Bocharova, Olga V., Bocharov, Eduard V., Kuznetsov, Andrey S., Kawecki, Charlotte, Bocquet, Olivier, Romier, Beatrice, Gorisse, Laetitia, Ghirardi, Maxime, Duca, Laurent, Blaise, Sébastien, Martiny, Laurent, Dauchez, Manuel, Efremov, Roman G., Debelle, Laurent
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137157/
https://ncbi.nlm.nih.gov/pubmed/27917893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38363
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