New Insights into Molecular Organization of Human Neuraminidase-1: Transmembrane Topology and Dimerization Ability

Neuraminidase 1 (NEU1) is a lysosomal sialidase catalyzing the removal of terminal sialic acids from sialyloconjugates. A plasma membrane-bound NEU1 modulating a plethora of receptors by desialylation, has been consistently documented from the last ten years. Despite a growing interest of the scient...

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Udgivet i:Sci Rep
Main Authors: Maurice, Pascal, Baud, Stéphanie, Bocharova, Olga V., Bocharov, Eduard V., Kuznetsov, Andrey S., Kawecki, Charlotte, Bocquet, Olivier, Romier, Beatrice, Gorisse, Laetitia, Ghirardi, Maxime, Duca, Laurent, Blaise, Sébastien, Martiny, Laurent, Dauchez, Manuel, Efremov, Roman G., Debelle, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137157/
https://ncbi.nlm.nih.gov/pubmed/27917893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38363
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