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Ubiquitin Ligase NEDD4 Regulates PPARγ Stability and Adipocyte Differentiation in 3T3-L1 Cells

Peroxisome proliferator–activated receptor-γ (PPARγ) is a ligand-activated nuclear receptor which controls lipid and glucose metabolism. It is also the master regulator of adipogenesis. In adipocytes, ligand-dependent PPARγ activation is associated with proteasomal degradation; therefore, regulation...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Li, Jing Jing, Wang, Ruishan, Lama, Rati, Wang, Xinjiang, Floyd, Z. Elizabeth, Park, Edwards A., Liao, Francesca-Fang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137149/
https://ncbi.nlm.nih.gov/pubmed/27917940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38550
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