RCANs regulate the convergent roles of NFATc1 in bone homeostasis

Activation of calcineurin-dependent nuclear factor of activated T cells c1 (NFATc1) is convergent for normal bone homeostasis. NFATc1 regulates both osteoclastogenesis and osteoblastogenesis. Here we investigated the roles of regulator of calcineurin (RCAN) genes in bone homeostasis. RCANs function...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kim, Jung Ha, Kim, Kabsun, Kim, Inyoung, Seong, Semun, Jeong, Byung-chul, Nam, Kwang-Il, Kim, Kyung Keun, Molkentin, Jeffery D., Kim, Nacksung
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137032/
https://ncbi.nlm.nih.gov/pubmed/27917924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38526
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