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RCANs regulate the convergent roles of NFATc1 in bone homeostasis

Activation of calcineurin-dependent nuclear factor of activated T cells c1 (NFATc1) is convergent for normal bone homeostasis. NFATc1 regulates both osteoclastogenesis and osteoblastogenesis. Here we investigated the roles of regulator of calcineurin (RCAN) genes in bone homeostasis. RCANs function...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Jung Ha, Kim, Kabsun, Kim, Inyoung, Seong, Semun, Jeong, Byung-chul, Nam, Kwang-Il, Kim, Kyung Keun, Molkentin, Jeffery D., Kim, Nacksung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137032/
https://ncbi.nlm.nih.gov/pubmed/27917924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38526
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