STAT5 is a key transcription factor for IL-3-mediated inhibition of RANKL-induced osteoclastogenesis

Among the diverse cytokines involved in osteoclast differentiation, interleukin (IL)-3 inhibits RANKL-induced osteoclastogenesis. However, the mechanism underlying IL-3-mediated inhibition of osteoclast differentiation is not fully understood. Here we demonstrate that the activation of signal transd...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lee, Jongwon, Seong, Semun, Kim, Jung Ha, Kim, Kabsun, Kim, Inyoung, Jeong, Byung-chul, Nam, Kwang-Il, Kim, Kyung Keun, Hennighausen, Lothar, Kim, Nacksung
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971530/
https://ncbi.nlm.nih.gov/pubmed/27485735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30977
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