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Questions and controversies: the role of necroptosis in liver disease

Acute and chronic liver injury results in hepatocyte death and turnover. If injury becomes chronic, the continuous cell death and turnover leads to chronic inflammation, fibrosis and ultimately cirrhosis and hepatocellular carcinoma. Controlling liver cell death both in acute injury, to rescue the l...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Dara, Lily, Liu, Zhang-Xu, Kaplowitz, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136616/
https://ncbi.nlm.nih.gov/pubmed/27924226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.89
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