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THE CONTRIBUTION OF ER STRESS TO LIVER DISEASES

The unfolded protein response (UPR) is an evolutionarily conserved cell signaling pathway which is activated to regulate protein synthesis and restore homeostatic equilibrium when the cell is stressed from increased client protein load or the accumulation of unfolded or malfolded proteins. Once acti...

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Detalhes bibliográficos
Main Authors: Dara, Lily, Ji, Cheng, Kaplowitz, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082587/
https://ncbi.nlm.nih.gov/pubmed/21384408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24279
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