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Differences in betaine-homocysteine methyltransferase expression, ER stress response and liver injury between alcohol-fed mice and rats

Chronic ethanol infusion resulted in greater serum ALT elevation, lipid accumulation, necroinflammation, and focal hepatic cell death in mice than rats. Mice exhibited a remarkable hyperhomocysteinemia but no increase was seen in rats. Similarly, a high methionine low folate diet (HMLF) induced less...

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Библиографические подробности
Главные авторы: Shinohara, Masao, Ji, Cheng, Kaplowitz, Neil
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840074/
https://ncbi.nlm.nih.gov/pubmed/20069651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23391
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