Aβ and Inflammatory Stimulus Activate Diverse Signaling Pathways in Monocytic Cells: Implications in Retaining Phagocytosis in Aβ-Laden Environment

Background: Accumulation of amyloid β (Aβ) is one of the main hallmarks of Alzheimer’s disease (AD). The enhancement of Aβ clearance may provide therapeutic means to restrict AD pathology. The cellular responses to different forms of Aβ in monocytic cells are poorly known. We aimed to study whether...

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Dades bibliogràfiques
Publicat a:Front Cell Neurosci
Autors principals: Savchenko, Ekaterina, Malm, Tarja, Konttinen, Henna, Hämäläinen, Riikka H., Guerrero-Toro, Cindy, Wojciechowski, Sara, Giniatullin, Rashid, Koistinaho, Jari, Magga, Johanna
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136556/
https://ncbi.nlm.nih.gov/pubmed/27994540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00279
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