Aβ and Inflammatory Stimulus Activate Diverse Signaling Pathways in Monocytic Cells: Implications in Retaining Phagocytosis in Aβ-Laden Environment

Background: Accumulation of amyloid β (Aβ) is one of the main hallmarks of Alzheimer’s disease (AD). The enhancement of Aβ clearance may provide therapeutic means to restrict AD pathology. The cellular responses to different forms of Aβ in monocytic cells are poorly known. We aimed to study whether...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Savchenko, Ekaterina, Malm, Tarja, Konttinen, Henna, Hämäläinen, Riikka H., Guerrero-Toro, Cindy, Wojciechowski, Sara, Giniatullin, Rashid, Koistinaho, Jari, Magga, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136556/
https://ncbi.nlm.nih.gov/pubmed/27994540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00279
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