Aβ and Inflammatory Stimulus Activate Diverse Signaling Pathways in Monocytic Cells: Implications in Retaining Phagocytosis in Aβ-Laden Environment

Background: Accumulation of amyloid β (Aβ) is one of the main hallmarks of Alzheimer’s disease (AD). The enhancement of Aβ clearance may provide therapeutic means to restrict AD pathology. The cellular responses to different forms of Aβ in monocytic cells are poorly known. We aimed to study whether...

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Publicado en:Front Cell Neurosci
Autores principales: Savchenko, Ekaterina, Malm, Tarja, Konttinen, Henna, Hämäläinen, Riikka H., Guerrero-Toro, Cindy, Wojciechowski, Sara, Giniatullin, Rashid, Koistinaho, Jari, Magga, Johanna
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136556/
https://ncbi.nlm.nih.gov/pubmed/27994540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00279
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