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Glutamatergic Neurotransmission in the Prefrontal Cortex Mediates the Suppressive Effect of Intra-Prelimbic Cortical Infusion of BDNF on Cocaine-Seeking

Cocaine self-administration induces dysfunctional neuroadaptations in the prefrontal cortex that underlie relapse to cocaine-seeking. Cocaine self-administration disturbs glutamatergic transmission in the nucleus accumbens that is prevented by infusion of brain-derived neurotrophic factor (BDNF) int...

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Veröffentlicht in:Eur Neuropsychopharmacol
Hauptverfasser: Go, Bok Soon, Barry, Sarah M., McGinty, Jacqueline F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136511/
https://ncbi.nlm.nih.gov/pubmed/27765467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2016.10.002
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