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Intra-Prelimbic Cortical Inhibition of Striatal Enriched Tyrosine Phosphatase Suppresses Cocaine Seeking in Rats

Cocaine self-administration in rats results in dysfunctional neuroadaptations in the prelimbic (PrL) cortex during early abstinence. Central to these adaptations is decreased phospho-extracellular signal-regulated kinase (p-ERK), which plays a key role in cocaine-seeking. Normalizing ERK phosphoryla...

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Bibliografiske detaljer
Udgivet i:Addict Biol
Main Authors: Siemsen, Ben M., Lombroso, Paul J., McGinty, Jacqueline F.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617773/
https://ncbi.nlm.nih.gov/pubmed/28349660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12504
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