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A Bayesian Dose-finding Design for Drug Combination Trials with Delayed Toxicities
We propose a Bayesian adaptive dose-finding design for drug combination trials with delayed toxicity. We model the dose-toxicity relationship using the Finney model, a model widely used in drug-drug interaction studies. The intuitive interpretations of the Finney model facilitate incorporating the a...
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| Publicado no: | Bayesian Anal |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5136476/ https://ncbi.nlm.nih.gov/pubmed/27924182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/13-BA839 |
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