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Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds

A central challenge of natural products research is assigning bioactive compounds from complex mixtures. The gold standard approach to address this challenge, bioassay-guided fractionation, is often biased towards abundant, rather than bioactive, mixture components. This study evaluated the combinat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Nat Prod
Main Authors: Kellogg, Joshua J., Todd, Daniel A., Egan, Joseph M., Raja, Huzefa A., Oberlies, Nicholas H., Kvalheim, Olav M., Cech, Nadja B.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135737/
https://ncbi.nlm.nih.gov/pubmed/26841051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.5b01014
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