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Opportunities and Limitations for Untargeted Mass Spectrometry Metabolomics to Identify Biologically Active Constituents in Complex Natural Product Mixtures

Compounds derived from natural sources represent the majority of small-molecule drugs utilized today. Plants, owing to their complex biosynthetic pathways, are poised to synthesize diverse secondary metabolites that selectively target biological macromolecules. Despite the vast chemical landscape of...

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Библиографические подробности
Опубликовано в: :J Nat Prod
Главные авторы: Caesar, Lindsay K., Kellogg, Joshua J., Kvalheim, Olav M., Cech, Nadja B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837904/
https://ncbi.nlm.nih.gov/pubmed/30844279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.9b00176
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