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Biochemometrics to Identify Synergists and Additives from Botanical Medicines: A Case Study with Hydrastis canadensis (Goldenseal)

A critical challenge in the study of botanical natural products is the difficulty of identifying multiple compounds that may contribute additively, synergistically, or antagonistically to biological activity. Herein, it is demonstrated how combining untargeted metabolomics with synergy-directed frac...

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Bibliographic Details
Published in:J Nat Prod
Main Authors: Britton, Emily R., Kellogg, Joshua J., Kvalheim, Olav M., Cech, Nadja B.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251718/
https://ncbi.nlm.nih.gov/pubmed/29091439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.7b00654
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