FMN2 makes perinuclear actin to protect nuclei during confined migration and promote metastasis

Cell migration in confined 3D tissue microenvironments is critical for both normal physiological functions and dissemination of tumor cells. We discovered a cytoskeletal structure that prevents damage to the nucleus during migration in confined microenvironments. The formin-family actin filament nuc...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Skau, Colleen T., Fischer, Robert S., Gurel, Pinar, Racine-Thiam, Hawa, Tubbs, Anthony, Baird, Michelle A., Davidson, Michael W., Piel, Matthieu, Alushin, Gregory M., Nussenzweig, Andre, Steeg, Patricia S., Waterman, Clare M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135586/
https://ncbi.nlm.nih.gov/pubmed/27839864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.10.023
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