FMN2 makes perinuclear actin to protect nuclei during confined migration and promote metastasis

Cell migration in confined 3D tissue microenvironments is critical for both normal physiological functions and dissemination of tumor cells. We discovered a cytoskeletal structure that prevents damage to the nucleus during migration in confined microenvironments. The formin-family actin filament nuc...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Skau, Colleen T., Fischer, Robert S., Gurel, Pinar, Racine-Thiam, Hawa, Tubbs, Anthony, Baird, Michelle A., Davidson, Michael W., Piel, Matthieu, Alushin, Gregory M., Nussenzweig, Andre, Steeg, Patricia S., Waterman, Clare M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135586/
https://ncbi.nlm.nih.gov/pubmed/27839864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.10.023
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