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Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments

Cell migration has two opposite faces: although necessary for physiological processes such as immune responses, it can also have detrimental effects by enabling metastatic cells to invade new organs. In vivo, migration occurs in complex environments and often requires a high cellular deformability,...

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發表在:Nat Commun
Main Authors: Thiam, Hawa-Racine, Vargas, Pablo, Carpi, Nicolas, Crespo, Carolina Lage, Raab, Matthew, Terriac, Emmanuel, King, Megan C., Jacobelli, Jordan, Alberts, Arthur S., Stradal, Theresia, Lennon-Dumenil, Ana-Maria, Piel, Matthieu
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796365/
https://ncbi.nlm.nih.gov/pubmed/26975831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10997
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