Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells

Prodigiosin, a natural red pigment produced by numerous bacterial species, has exhibited promising anticancer activity; however, the molecular mechanisms of action of prodigiosin on malignant cells remain unclear. Aberrant activation of the Wnt/β-catenin signaling cascade is associated with numerous...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wang, Zhongyuan, Li, Bo, Zhou, Liang, Yu, Shubin, Su, Zijie, Song, Jiaxing, Sun, Qi, Sha, Ou, Wang, Xiaomei, Jiang, Wenqi, Willert, Karl, Wei, Lei, Carson, Dennis A., Lu, Desheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135380/
https://ncbi.nlm.nih.gov/pubmed/27799526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616336113
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